This paper describes the architecture of the first implementation of the In-VIGO grid-computing system. The architecture is designed to support computational tools for engineering and science research In Virtual Information Grid Organizations (as opposed to in vivo or in vitro experimental research). A novel aspect of In-VIGO is the extensive use of virtualization technology, emerging standards for grid-computing and other Internet middleware. In the context of In-VIGO, virtualization denotes the ability of resources to support multiplexing, manifolding and polymorphism (i.e. to simultaneously appear as multiple resources with possibly different functionalities). Virtualization technologies are available or emerging for all the resources needed to construct virtual grids which would ideally inherit the above mentioned properties.
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