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Real-Time Linux Dynamic Clamp: A Fast and Flexible Way to Construct Virtual Ion Channels in Living Cells

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21 out of 46 users found this white paper useful


Publisher Biomedical Engineering Society
Publisher Registration N/A
Topics Linux - Open Source, Linux Server OS Date added 18 Jul 2001
Downloads 18 Format 1.0MB PDF

This paper describes a system for real-time control of biological and other experiments. This device, based around the Real-Time Linux operating system, was tested specifically in the context of dynamic clamping, a demanding real-time task in which a computational system mimics the effects of nonlinear membrane conductances in living cells. The system is fast enough to represent dozens of nonlinear conductances in real time at clock rates well above 10 kHz. Conductances can be represented in deterministic form, or more accurately as discrete collections of stochastically gating ion channels.

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21 out of 46 users found this white paper useful


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