| Publisher | SAS Institute | ||
|---|---|---|---|
| Format | 209.7KB PDF | Date added | 28 Feb 2006 |
| Topics | Knowledge and Data Management, Data Mining - Analysis | ||
| Downloads | 166 | ||
This paper gives an exposition of recently developed methods of estimating the False Discovery Rate (FDR) under multiple comparisons and discusses their implementation using SAS. For example, microarray experiments typically involve tests of significance for hundreds or thousands of genes. For biologists confronted by this problem of multiplicity, the FDR is an appealing quantification of error. SAS code using the SAS/MACRO, SAS/STAT, and SAS/IML facilities is presented to compute this estimate, and appears in the appendix. Q-values, which are to FDR as p-values are to the type I error rate, are also obtained and used to reproduce plots generated by the R package "Qvalue" that may be helpful for conducting multiple tests.
Did you find this white paper useful?
22 out of 50 users found this white paper useful
Related white papers
The Journey Along an Information-Led Transformation
A shift is underway from simple automation to business optimization, and information is at the center of it. Information, when aligned with your business strategy, holds the key to driving profitable...
The new information agenda:Do you have one?
The lack of trusted information — information that is accurate, timely and relevant— is on the minds of CEOs and senior executives around the world. a paradigm shift from siloed...
Best Practices for Translating Customer Satisfaction into Revenue
Today's support organisations are focused on two top-level metrics: financial results and customer satisfaction. For most, it's easy to track financial performance, but customer satisfaction is akin to speaking a...
Support Strategies: Customer Experience Management
Customer experience is the most powerful tool available today for distinguishing your company from competitors ? each contact with the customer offers an opportunity for strengthening your relationships by delivering...
3 Strategies for Reducing IT Support Costs
As companies brace for more bumps in the economic downturn, many organisations are indiscriminately cutting costs. To ensure a seamless transition into the post-recession market, however, slashing and burning is...
Forrester Strategies for Assessing IT Business Satisfaction
If you aren't assessing customer satisfaction you are overlooking a potential goldmine. This valuable data is crucial to creating a successful IT strategy. But where do you start? This new...
Realising the benefits of going green
Cross over to greener communications with improved data accuracy. Many organisations have processes in place to improve the quality of their contact data to address business drivers, such as cost reduction...
