This program recommendation describes problems in automating DNA analysis. The presented solution involves the application of automation technology from the semiconductor area to the area of large-scale DNA analysis. The proposed program would significantly impact basic DNA analysis and will provide substantial long term solutions to the recurring demand for the analysis of DNA molecules from different sources resulting from diagnostic, agricultural and environmental analysis. The proposed automation would impact broad areas of DNA typing ranging from highly specific DNA fingerprinting, monitoring individual DNA samples for retrovirus infection, and in monitoring environmental quality.
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