The drug development industry is undergoing dramatic changes. Genomics and combinatorial chemistry technologies have revolutionized how we study the underlying causes of disease, and have given us new tools to identify and develop novel disease therapies. These new tools have dramatically increased the number of potential disease targets and drug candidates. The increase in capacity and efficiency in these areas is widely believed to be the source for the novel discoveries that will continued to drive the economic growth of the pharmaceutical industry. Unfortunately, our capacity to "validate" potential disease targets for drug development, or to test potential drugs for efficacy and toxicity, has not kept up with this pace. It is these areas that are now significant bottlenecks.
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